Shrimp & Eczema
Heat-stable allergen shared across all crustaceans (shrimp, crab, lobster). A key link: dust mite sensitisation through eczema skin can prime the immune system to later react to shellfish. Does not cross-react with fish.
4/5
Reaction Timeline
Shrimp reactions are predominantly immediate and can be severe (anaphylaxis). Cooking vapors and steam from boiling shrimp can trigger airborne reactions in highly sensitized individuals.
How Much Is Needed To React?
Trace amounts can trigger reactions in sensitized individuals. Cross-contact from shared cooking oil, grills, and fryers in restaurants is a major risk. If you have dust mite allergy AND eczema, shellfish sensitization is particularly likely.
Does Preparation Matter?
Tropomyosin is heat-stable — cooking does NOT reduce allergenicity. Boiling, grilling, frying, or baking shrimp all retain full allergenic potential. In fact, cooking may enhance allergenicity by concentrating proteins. Even the steam from cooking shrimp can be enough to trigger reactions. [1][2]
Also Watch Out For...
Crab — 92–98% tropomyosin amino acid homology; clinically co-reactive [1]
Lobster — 92–98% tropomyosin homology; clinically co-reactive [1]
House dust mite — ~80% tropomyosin homology (Der p 10); likely primary sensitizer in humid climates [2]
Cockroach — tropomyosin cross-reactivity (Bla g 7)
Mollusks (squid, clams, mussels) — only ~14% clinical cross-reactivity despite tropomyosin presence
Insects — tropomyosin cross-reactivity (relevant for insect-protein foods)
What To Use Instead
White fish (cod, tilapia) — NO cross-reactivity between shellfish and finfish
Chicken (for stir-fries and curries)
Tofu (for Asian dishes — note: soy is on the trigger list)
Hearts of palm ("lobster roll" substitute in some recipes)
Hidden Sources
Fish sauce (may contain shrimp)
Shrimp paste in Thai/Southeast Asian curries
Fried rice and stir-fries (shared wok/oil in restaurants)
Caesar dressing (some contain anchovies, not shrimp — but shared kitchen risk)
Glucosamine supplements (often shrimp-shell derived)
Surimi/imitation crab (may contain shrimp)
Dim sum and dumplings (shared steamers)
Paella and bouillabaisse
Chitin in some wine/beer clarification
Insect-based protein products (cross-reactive tropomyosin)







