Sesame seeds & Eczema
Now the 9th mandatory US allergen label due to severe reaction potential. Heat-stable — roasting doesn't reduce the risk. Found in tahini, hummus, burger buns, and Asian sauces.
4/5
Reaction Timeline
Sesame reactions are predominantly immediate and can be severe. Anaphylaxis is well-documented. Delayed eczema flares are less commonly reported than with milk or egg.
How Much Is Needed To React?
Sesame allergy can be triggered by trace amounts. Cross-contact from bakery products (sesame-topped buns processed on same lines as plain buns) is a major risk. Some US manufacturers added sesame TO products post-FASTER Act to simplify labeling — always check labels.
Does Preparation Matter?
Ses i 1 (2S albumin) is heat-stable and digestion-resistant. Roasting, toasting, or baking sesame seeds does NOT meaningfully reduce allergenicity. Tahini (ground paste) and sesame oil (cold-pressed) retain full allergenic potential. Highly refined sesame oil may have reduced protein content, but data are limited and it is not considered safe for allergic individuals. [1]
Also Watch Out For...
Peanut — ~40% of sesame-allergic individuals react to peanuts; Ses i 3 shares ~80% homology with Ara h 1 [1]
Poppy seeds — sesame-poppy seed cross-reactivity documented (Vocks et al., 1993) [3]
Kiwi — sesame-poppy-kiwi cross-reactivity syndrome [3]
Other tree nuts — variable co-sensitization via shared 2S albumin protein family
What To Use Instead
Sunflower seed butter (for tahini substitute in dressings)
Pumpkin seed butter (for spreads)
Hemp seeds (for garnish/topping)
Avocado-based dressings instead of tahini-based (note: avocado is on the trigger list)
Hidden Sources
Tahini (sesame paste — in hummus, halva, dressings)
Hummus (tahini is a key ingredient)
Sesame oil (cold-pressed retains protein; refined may be tolerated)
Burger buns and bagels (sesame-topped, cross-contact risk on plain items)
Falafel (often rolled in sesame)
Asian stir-fry sauces
Gomashio (Japanese sesame salt)
Energy bars and granola
Sushi rolls with sesame coating
Some cosmetics and soaps (sesame oil)







