Paprika is dried, ground sweet pepper that can trigger eczema through both skin contact sensitisation and immune-mediated allergy. It is part of a well-established cross-reactivity pattern called celery-mugwort-spice syndrome — people allergic to mugwort pollen or celery may also react to paprika and other spices. In studies of people with spice allergies, about 19% tested positive to paprika.

It also contains some capsaicin (less than hot peppers) that can irritate skin. Paprika hides in many spice blends including chilli powder, curry powder, Cajun seasoning, and BBQ rubs. Chorizo, flavoured crisps, and many processed meats use paprika for colour and flavour — making it easy to consume without realising it.